Research paper on viruses

Wild animals have their own epidemics, which are called epizootics, as well as circulating diseases like colds or flus in humans. Overviews of epizootic prevalence in animals are rare in the literature, but epizootics are common in nature. Some epizootics are traced to spillover events. Much of the existing research on spillover in wild animals is on topics of human health or veterinary interest, e.

Research paper on viruses

Research paper on viruses

The researchpublished June 21 in Neuron, found convincing signs that certain types of herpes virus may promote the complex process that leads to the disease that afflicts some 5.

The long-standing amyloid hypothesis posits that symptoms are triggered by the buildup of amyloid beta brain plaques, but trials of drugs that attempt to clear these plaques have so far flopped. Skeptical researchers have hunted for other explanations, and some have zeroed in on microbes.

Joel Dudley, a geneticist and genomic scientist at the Icahn School of Medicine at Mount Sinai and senior author of the new paper, had not intended to investigate this theory when his lab began working on the newly published study in HHV-6A is a usually symptom-less virus that infects people later in life.

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HHV-7 infects more than 80 percent of infants, often causing a rash. To probe this question, the team created the equivalent of a biological social network to probe how various molecular and genetic signals were interacting with each other.

When they later bred mice deficient in this microRNA, they found that the rodents developed larger and more abundant amyloid plaques in their brains than did mice with normal microRNA levels. It might be possible to use certain biological markers of the viruses to identify high-risk individuals.

A series of studies led by Massachusetts General Hospital neurologist Robert Moir and colleagues suggests a possible theory to bind these disparate pathogen findings together: Beta amyloid proteins may accumulate in the brain as part of an immune response against injury or invading pathogens.

In a paper published online on June 21st, also in Neuron, Moir and colleagues reported that amyloid beta peptides bind to and entrap HSV-1 and HHV-6, thereby helping to protect against infection.

Mice infected with these herpes viruses quickly accumulate beta amyloid plaques, too.

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Their theory posits that when enough beta amyloid plaques build up during an infection, they then trigger inflammation and other unhelpful responses, such as the creation of tau tangles that kill neurons.

The plaques also alert brain immune cells called microglia to the fact that something is wrong; these cells launch an immune cascade that kills even more neurons.

Research paper on viruses

Strengthening the evidence for this controversial idea will be difficult. Ruth Itzhaki, a neurobiologist at the University of Manchester in the U. But Dudley is willing to accept the risks and push forward.The reason why HIV cannot be cured by current therapy is because of viral persistence in resting T cells.

One approach to permanent HIV remission that has received less attention is . Dec 19,  · A colorized electron micrograph of the coronavirus that causes Middle East respiratory syndrome, or MERS. Federal officials ended a moratorium imposed on funding research that alters viruses .

Viruses, an international, peer-reviewed Open Access journal. History. In Jürg Tschopp and his group published a paper on their discovery of granzymes. In the paper they discussed how they purified, characterized and discovered a variety of granzymes found within cytolytic granules that were carried by cytotoxic T lymphocytes and natural killer cells. mBio ® is ASM's first broad-scope, online-only, open access journal. mBio offers streamlined review and publication of the best research in microbiology and allied fields.. For Authors. ASM Author Center; Board of Editors; Policies; Publication Fees; AAM Fellows.

MHRP researchers and Thai collaborators are leading the way in acute infection studies. One study, called RV/SEARCH is providing knowledge about the earliest HIV events that may provide clues to developing an effective HIV vaccine or even help identify ways to achieve a functional cure.

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Get Started. Going Viral. Einstein scientists are turning to some big ideas to confront some of nature’s tiniest killers: the viruses that cause Ebola, herpes, chikungunya and dengue fever.

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